Product Descriptions

HAqua-7
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HAqua-7

Hyaluronic Acid with very low Mw

It is oligomeric hyaluronic acid with less than 5KDa of Mw. HAqua-7 shows high expression of aquaporin 3 mRNA and protein in HaCaT cell so that it shows high moisturizing effect in clinical test.

HAqua-7 has also anti-inflammation effect by inhibition of NF-kB which plays a key role in skin inflammation.

Characteristics of HAqua-7

  • 13C-NMR Spectrum

    It shows characteristic peaks of Low Mw of hyaluronic acid

  • GPC Chromatogram(LALLS)

    Molecular weight of HAqua-7 is less than 5kDa

Efficacies of HAqua-7 for Cosmetic Application

1) Skin moisturizing effect followed by increase of expression of aquaporin 3 mRNA and proteins in HaCaT cell.
2) Skin homeosis and anti-aging effect by keeping excellent skin moisturizing effect(clinical).
3) Skin anti-inflammation effect by suppression of NO production and inhibition of expression of NF-kB.

  • Increase of Aquaporin 3 Expression in HaCaT cell
  • Anti-inflammatory effect(in vitro)
  • Cell Viability(in vitro)
  • Skin moisturizing effect(Clinical)

Specification

Analytical Tests Specificatitons
INCI Name Hyaluronic Acid
Appearance pale yellow liquid
Glucouronic Acid ≥0.44%
Dry Residue ≥1.0%
pH(neat) 4.0~6.0
Molecular Weight ≤10,000Da
Protein ≤0.01%
Heavy Metals ≤10ppm
Arsenic ≤2ppm
Total Bacterial Count ≤100cfu/g

※ Recommanded Dosage for Cosmetic Application 1~3% for face and body, 2~5% for hair